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Magnesium, the Missing Link Essential for Health

By on April 30, 2017
Magnesium rich foods avocado, spinach, almonds, beans, pumpkin seeds in bowls

Those suffering from chronic pain, spasms, lower back pain, insomnia, diabetes and migraines may have one thing in common – a severe magnesium deficiency. In fact, magnesium deficiency is prevalent among 80% of North Americans.1   

Sadly, these deficiencies may be contributing to a host of chronic and inflammatory diseases and impacting their quality of life. Nutrient-depleted soils, medications, and stress all contribute to magnesium deficiency. But this research is not new. It was already determined by the National Research Council back in the late 80’s.


Chart tracking magnesium deficiencies

The answer is magnesium supplementation. Today, magnesium is being recognized and labeled the mineral superstar. It is the body’s muscle relaxant and helpful in all chronic inflammatory diseases. Why? New research shows better absorption of the mineral by binding with the amino acid l-glycine offers more effective supplementation support for deficiencies.

Magnesium for Inflammation

Magnesium is an essential mineral responsible for over 300 enzymatic activities and co-factors in the body. It’s crucial for the synthesis of DNA and RNA, muscle and nerve function, blood sugar and blood pressure regulation.2  So, it’s no surprise that the epidemic of chronic inflammatory diseases correlate to magnesium deficiency, yet it is still often dismissed by many mainstream health practitioners.

Determining Magnesium Deficiency and Deficiency Symptoms

The most common test performed to determine a magnesium deficiency is called the Magnesium Serum Test. However, there is 50% to 60% of magnesium present in the bones and soft tissues and only less than 1% in blood serum.2 Furthermore, the body tries to maintain blood levels at the cost of the bones and soft tissues, making magnesium deficiency difficult to properly determine through bloodwork.

If you experience any of these symptoms below, you could be magnesium deficient. The more conditions you can check off, the more likely it is that you are deficient.

  • Neuropathies
  • Chronic pain
  • Fibromyalgia
  • High Blood Pressure
  • Insomnia
  • Arrhythmia
  • Diabetes
  • Migraines
  • Restless leg syndrome
  • Muscle spasms & PMS cramping
  • Chronic constipation

Choosing the Best Quality Magnesium

Magnesium can be found in many forms: Magnesium Oxide, Magnesium Citrate and Magnesium Glycinate are among the most popular. However, not all magnesium forms are considered equal. Magnesium Glycinate has prevailed over other forms of magnesium because it’s the highest absorbable form of magnesium on the market, it is best tolerated, and the Glycine portion has calming and countless nutritional properties on its own.

Magnesium Oxide is commonly used for its laxative effects. Known more commonly as “Milk of Magnesia”, it is barely absorbed, but rather draws water molecules to the colon, creating a flushing effect, taking magnesium and other essential minerals along with it. In contrast, Magnesium Glycinate is highly bioavailable, thus, replenishing magnesium stores and fixing constipation from the “inside”.

Magnesium Citrate is still being used for GI flushing as preparation for endoscopic treatments. Additionally, citrate is produced during the Citric Acid Cycle (Krebs Cycle), the body’s energy production cycle, and can technically be considered a form of metabolic waste.

Magnesium Glycinate is absorbed, like other minerals, through the intestinal wall. But, when bound to the amino acid l-glycine, it also gets collected by amino acid “scavengers” and absorbed through a process called “Active Transport”. These “scavengers” search for protein forming amino acids inside the bowels and when they find one, in this case l-glycine, they link up and actively carry it through the cell membranes into the blood. Magnesium bound to L-Glycine gets taken along.4

Magnesium Dosing:

Health Canada recommends 420mg of magnesium (elemental) daily. When searching for a Magnesium Glycinate be sure to look for one with the highest label dosage closest to the RDA or slightly above. Pure Lab Vitamins’ Magnesium Glycinate, will provide you with 495 mg of magnesium daily – the only Canadian company licensed to provide 75mg above the RDA, to help replenish deep tissues.

Mangesium Glycinate product shot from Pure Lab

Keep in mind, many individuals are significantly depleted and may require even more initially, to provide the daily requirements plus enough to replenish deep tissues. In this case, it’s recommended to speak with a healthcare practitioner for therapeutic dosing.


  1. National Research Council. Recommended dietary allowances, 10th ed. Washington, DC: National Academy Press, 1989:187-194.
  3. Magnesium, PO Wester, MD, Am J Clin Nutr 1987;45:1305-12
  4. Schuette SA, Lashner BA, Janghorbani M (1994) Bioavailability of magnesium diglycinate vs magnesium oxide in patients with ileal resection.JPEN J Parenter Enteral Nutr 18: 430-435

About Charleen Wyman


  1. Lynette

    November 29, 2017 at 6:37 pm

    Does anyone know where I can buy Pure Lab Magnesium Glycinate Highest Daily Dose 495 mg online!
  2. Charleen Wyman

    December 4, 2017 at 10:04 am

    I think you can purchase direct from their site.
  3. Anna O'Byrne

    December 4, 2017 at 10:20 pm

    It is actually not true that magnesium glycinate is more absorbable. There are no peer-reviewed, published studies comparing magnesium glycinate to magnesium citrate. What indirect evidence exists suggests that the two are comparable, with a possible advantage for magnesium citrate.

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